Efficacy and Safety of Anticoagulants in Patients with Atrial Fibrillation and History of Falls or Risk of Falls: A Systematic Review and Multilevel Meta-Analysis.

Thibaut GalvainRuaraidh HillSarah DoneganPaulo LisboaGregory Y H LipGabriela Czanner

Published in: Drug safety (2022)

NOACs were associated with less intracranial hemorrhages and ischemic strokes/systemic embolisms than VKAs in AF patients at risk of falls. These findings suggesting preferred use of NOACs over VKAs have clinical implications for physicians, patients and policy makers.

Keyphrases

systematic review
end stage renal disease
ejection fraction
newly diagnosed
primary care
chronic kidney disease
healthcare
public health
community dwelling
mental health
meta analyses
patient reported outcomes
subarachnoid hemorrhage
case control
patient reported