Optimized angiotensin-converting enzyme activity assay for the accurate diagnosis of sarcoidosis.

Alexandra CsongrádiAttila EnyediIstván TakácsTamás VéghIvetta S MányinéZsófia PólikIstván Tibor AltorjayJózsef BallaGyörgy BallaIstván ÉdesJános KappelmayerAttila TóthZoltán PappMiklós Fagyas

Published in: Clinical chemistry and laboratory medicine (2019)

An optimized fluorescent kinetic assay of serum ACE activity combined with ACE I/D genotype determination is an alternative to invasive biopsy for confirming the diagnosis of sarcoidosis in a significant percentage of patients.

Keyphrases

angiotensin converting enzyme
angiotensin ii
end stage renal disease
high throughput
chronic kidney disease
newly diagnosed
ejection fraction
prognostic factors
peritoneal dialysis
ultrasound guided
solid phase extraction
patient reported
simultaneous determination
fluorescent probe