Antioxidants and α-glucosidase inhibitors from Neptunia oleracea fractions using 1H NMR-based metabolomics approach and UHPLC-MS/MS analysis.
Soo Yee LeeAhmed MedianiIntan Safinar Ismailnull MaulidianiFaridah AbasPublished in: BMC complementary and alternative medicine (2019)
The findings of this work supported that N. oleracea is a rich source of phenolics that can be potential antioxidants and α-glucosidase inhibitors for the management of diabetes. To our knowledge, this study is the first report on the metabolite-bioactivity correlation and UHPLC-MS/MS analysis of N. oleracea fractions.
Keyphrases
- ms ms
- liquid chromatography tandem mass spectrometry
- molecular docking
- type diabetes
- cardiovascular disease
- mass spectrometry
- magnetic resonance
- healthcare
- high resolution
- ultra high performance liquid chromatography
- high performance liquid chromatography
- glycemic control
- adipose tissue
- solid phase extraction
- climate change
- liquid chromatography
- weight loss