Stem Cell Therapy for Repair of the Injured Brain: Five Principles.

Published in: The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry (2022)

Cell therapy holds great promise for regenerative treatment of disease. Despite recent breakthroughs in clinical research, applications of cell therapies to the injured brain have not yielded the desired results. We pinpoint current limitations and suggest five principles to advance stem cell therapies for brain regeneration. While we focus on cell therapy for stroke, all principles also apply for other brain diseases.

Keyphrases

cell therapy
stem cells
resting state
white matter
cerebral ischemia
mesenchymal stem cells
single cell
subarachnoid hemorrhage
big data
bone marrow
brain injury
artificial intelligence
smoking cessation
replacement therapy