Different prognostic role of EGFR mutation according to the IASLC histologic grade in patients with resected early-stage lung adenocarcinoma.
Tae Hee HongSoohyun HwangYoon-La ChoiGenehee LeeSehhoon ParkMyung-Ju AhnYoonseo LeeYeong Jeong JeonJunghee LeeSumin ShinSeong Yong ParkJong Ho ChoYong Soo ChoiJhingook KimYoung Mog ShimJuhee ChoHong Kwan KimPublished in: Histopathology (2023)
EGFR mutation status was associated with a risk of recurrence after consideration of the IASLC histologic grading, especially in G3 tumors. The results of this study would be useful for developing a new staging system and identifying a subset of patients who may benefit from adjuvant targeted therapy.