GIMAP7 inhibits epithelial-mesenchymal transition and glycolysis in lung adenocarcinoma cells via regulating the Smo/AMPK signaling pathway.

Liyuan CuiYumei ShenShanzhou DuanQifeng DingYifei WangWentao Yang Yongbing Chen

Published in: Thoracic cancer (2023)

These results demonstrate that GIMAP7 could inhibit cell proliferation, mobility and glycolysis, but accelerate apoptosis via repressing the Smo/AMPK signaling pathway in LUAD.

Keyphrases

cell cycle arrest
pi k akt
signaling pathway
epithelial mesenchymal transition
induced apoptosis
cell proliferation
endoplasmic reticulum stress
skeletal muscle
transforming growth factor
oxidative stress
protein kinase
cell cycle