Maternal Diet Quality and the Health Status of Newborns.
Jitka PavlikovaAntonin AmbrozKaterina HonkovaIrena ChvojkovaRadim J SramPavel RossnerJan TopinkaTomas GramblickaOndrej ParizekDenisa ParizkovaJana SchmuczerovaJana PulkrabovaAndrea RossnerovaPublished in: Foods (Basel, Switzerland) (2022)
The maternal diet during pregnancy affects neonatal health status. The objective of this study was to assess the nutritional quality of the maternal diet, and its contamination by persistent organic pollutants (POPs), in pregnant women living in two areas of the Czech Republic with different levels of air pollution, and subsequently to assess the relationship of these two factors with birth weight and neonatal oxidative stress. To determine the level of oxidative stress, 8-isoprostane concentrations in umbilical cord plasma were measured. The overall nutritional quality of the maternal diet was not optimal. Of the nutritional factors, protein intake proved to be the most significant showing a positive relationship with birth weight, and a negative relationship with the oxidative stress of newborns. Dietary contamination by persistent organic pollutants was low and showed no statistically significant relationship with birth weight. Only one of the 67 analyzed POPs, namely the insecticide dichlorodiphenyltrichloroethane (DDT), showed a statistically significant positive relationship with the level of neonatal oxidative stress.
Keyphrases
- birth weight
- gestational age
- oxidative stress
- weight gain
- pregnant women
- weight loss
- preterm birth
- physical activity
- air pollution
- dna damage
- mesenchymal stem cells
- umbilical cord
- body mass index
- ischemia reperfusion injury
- induced apoptosis
- diabetic rats
- drinking water
- bone marrow
- quality improvement
- cystic fibrosis
- pregnancy outcomes
- signaling pathway
- chronic obstructive pulmonary disease
- endoplasmic reticulum stress
- heat stress