Filtrated Adipose Tissue-Derived Mesenchymal Stem Cell Lysate Ameliorates Experimental Acute Colitis in Mice.
Takahiro NishikawaKeiko MaedaMasanao NakamuraTakeshi YamamuraTsunaki SawadaYasuyuki MizutaniTakanori ItoTakuya IshikawaKazuhiro FurukawaEizaburo OhnoRyoji MiyaharaHiroki KawashimaTakashi HondaMasatoshi IshigamiTokunori YamamotoSeiji MatsumotoYuji HottaMitsuhiro FujishiroPublished in: Digestive diseases and sciences (2020)
FADSTL effects were dependent on its administration frequency, suggesting the requirement of continuous FADSTL administration. FADSTL improved colitis by maintaining the intestinal barrier function through its anti-inflammatory and anti-apoptotic actions.
Keyphrases
- anti inflammatory
- adipose tissue
- mesenchymal stem cells
- liver failure
- cell death
- ulcerative colitis
- respiratory failure
- insulin resistance
- bone marrow
- high fat diet induced
- high fat diet
- drug induced
- mouse model
- umbilical cord
- type diabetes
- intensive care unit
- stem cells
- hepatitis b virus
- skeletal muscle
- extracorporeal membrane oxygenation
- acute respiratory distress syndrome