Longitudinal relation between structural network efficiency, cognition, and gait in cerebral small vessel disease.
Mengfei CaiMina A JacobDavid G NorrisFrank-Erik de LeeuwAnil M TuladharPublished in: The journals of gerontology. Series A, Biological sciences and medical sciences (2021)
We found that disruption of the white matter structural network was associated with gait decline over time, while the effect of cognitive decline was not. This suggests that structural network disruption has an important role in explaining the pathophysiology of gait decline in older patients with SVD, independent of cognitive decline.