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MRI analysis of neurodevelopmental anatomy in myelomeningocele: prenatal vs postnatal repair.

A K BruzekGretchen M KollerSasidhar KarupartiK VaragurA DunbarT M FlandersM MingoK SudanaguntaKatherine H BligardAnthony O OdiboJ VrecenakA MianJ M Strahle
Published in: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (2024)
We report baseline variations in developmental neuroanatomy in patients with MMC including rates of CC dysgenesis, gray matter heterotopia and additional cranial and spinal MRI findings. We found that prenatal surgery results in changes to infratentorial anatomy, with minimal effect on supratentorial brain development. This information will be useful in myelomeningocele counseling and in understanding how prenatal repair of myelomeningocele affects brain development. This article is protected by copyright. All rights reserved.
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