Proton pump inhibitors co-prescribed with warfarin reduce warfarin control as measured by time in therapeutic range.

Victoria BertramKelly YeoShailendra Anoopkumar-Dukie Nijole Bernaitis

Published in: International journal of clinical practice (2019)

Patients taking PPIs with warfarin had significantly lower TTRs and higher incidence of minor bleeds. This combination warrants additional caution and monitoring with warfarin control as measured by TTR potentially affected.

Keyphrases

atrial fibrillation
direct oral anticoagulants
venous thromboembolism
oral anticoagulants
end stage renal disease
newly diagnosed
chronic kidney disease
peritoneal dialysis
prognostic factors