Development of a high-throughput SARS-CoV-2 antibody testing pathway using dried blood spot specimens.
Stuart J MoatWioleta M ZelekEmily CarneMark James PonsfordKathryn BramhallSara JonesTariq El-ShanawanyMatt P WiseAnnette ThomasChloe GeorgeChristopher FeganRachael StevenRussell WebbIan WeeksB Paul MorganStephen JollesPublished in: Annals of clinical biochemistry (2020)
SARS-CoV-2 IgG receptor-binding domain antibodies can be reliably detected in DBS specimens. DBS serological testing offers lower costs than either point of care or serum/plasma assays that require patient travel, phlebotomy and hospital/clinic resources; the development of a DBS assay may be particularly important for resource poor settings.