Development of a high-throughput SARS-CoV-2 antibody testing pathway using dried blood spot specimens.

Stuart J MoatWioleta M ZelekEmily CarneMark James PonsfordKathryn BramhallSara JonesTariq El-ShanawanyMatt P WiseAnnette ThomasChloe GeorgeChristopher FeganRachael StevenRussell WebbIan WeeksB Paul MorganStephen Jolles

Published in: Annals of clinical biochemistry (2020)

SARS-CoV-2 IgG receptor-binding domain antibodies can be reliably detected in DBS specimens. DBS serological testing offers lower costs than either point of care or serum/plasma assays that require patient travel, phlebotomy and hospital/clinic resources; the development of a DBS assay may be particularly important for resource poor settings.

Keyphrases

sars cov
high throughput
deep brain stimulation
respiratory syndrome coronavirus
primary care
healthcare
single cell
binding protein
dna binding
drug induced