Functional outcomes and survival after surgical stabilization for inoperable non-small-cell lung cancer with spinal metastasis of the thoracic and lumbar spines: a retrospective comparison between epidermal growth factor receptor-tyrosine kinase inhibitor and platinum-based chemotherapy groups.
Hsi-Hsien LinChao-Hua ChiuPo-Hsin ChouHsiao-Li MaJung-Pan WangShih-Tien WangChien-Lin LiuMing-Chau ChangPublished in: Spinal cord (2019)
Surgical stabilization with or without laminectomy improved functional outcomes in patients with inoperable non-small-cell lung cancer, and post-operative functional outcomes were similar between chemotherapy and targeted therapy groups. A longer survival was observed with targeted therapy for the patients whose NSCLC was diagnosed before spinal metastasis, however, the longer survival was not statistically significant.
Keyphrases
- epidermal growth factor receptor
- locally advanced
- spinal cord
- advanced non small cell lung cancer
- end stage renal disease
- tyrosine kinase
- ejection fraction
- small cell lung cancer
- chronic kidney disease
- minimally invasive
- peritoneal dialysis
- prognostic factors
- free survival
- squamous cell carcinoma
- spinal cord injury
- drug delivery
- cancer therapy
- chemotherapy induced