Enantioselective α-Carbonylative Arylation for Facile Construction of Chiral Spirocyclic β,β'-Diketones.

We herein describe the first enantioselective α-carbonylative arylation, providing a diverse set of chiral spiro β,β'-diketones bearing various ring sizes and functionalities in high yields and good to excellent enantioselectivities. Calculations suggest the transformation proceeds through reductive elimination instead of nucleophilic addition pathway.