Mono- and multimeric PSMA-targeting small molecule-thorium-227 conjugates for optimized efficacy and biodistribution in preclinical models.
Niels BöhnkeBård IndrevollStefanie HammerAlex PappleAlexander KristianHans BriemArif CelikDominik MumbergAlan CuthbertsonSabine Zitzmann-KolbePublished in: European journal of nuclear medicine and molecular imaging (2023)
Monomeric and multimeric PSMA SMOL-TTCs show high tumor uptake and fast clearance in preclinical models and warrant further therapeutic exploration.