Re-irradiation for recurrent glioma: outcome evaluation, toxicity and prognostic factors assessment. A multicenter study of the Radiation Oncology Italian Association (AIRO).

Pierina NavarriaGiuseppe MinnitiElena ClericiStefano TomatisValentina PinziPatrizia CiammellaMarco GalaverniDante AmelioDaniele ScartoniSilvia ScocciantiMarco KrengliLaura MasiniLorena DraghiniErnesto MaranzanoValentina BorzilloPaolo MutoFabio FerrareseLaura FariselliLorenzo LiviFrancesco PasqualettiAlba FiorentinoFilippo AlongiMichela Buglione di MonaleStefano MagriniMarta Scorsetti

Published in: Journal of neuro-oncology (2018)

our data underline re-RT as a safe and feasible treatment with limited rate of toxicity, and a combined ones as a better option for selected patients. The identification of a BED threshold able to obtain a greater benefit on OS, can help in designing future prospective studies.

Keyphrases

prognostic factors
end stage renal disease
oxidative stress
ejection fraction
chronic kidney disease
newly diagnosed
radiation therapy
radiation induced
combination therapy
replacement therapy
case control
artificial intelligence