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Anti-Pneumococcal Vaccine-Induced Cellular Immune Responses in Post-Traumatic Splenectomized Individuals.

Djursun KarasartovaUmut GaziOzgur TosunAyse S GureserIbrahim T SahinerMete DolapciAysegul T Ozkan
Published in: Journal of clinical immunology (2017)
According to our data, splenectomy negatively influences the levels of PCV-induced lymphoproliferation, TH1 differentiation, and cytokine release. Besides, PCV failed to induce TH17-dominant immune response which is crucial for protection against extracellular pathogens.
Keyphrases
  • immune response
  • high glucose
  • diabetic rats
  • dendritic cells
  • machine learning
  • big data
  • deep learning
  • antimicrobial resistance