Three-Dimensional Evaluation of Isodose Radiation Volumes in Cases of Severe Mandibular Osteoradionecrosis for the Prediction of Recurrence after Segmental Resection.
Haye H GlasJoep KraeimaSilke TribiusFrank K J LeusinkCarsten RendenbachMax HeilandCarmen StrombergerAshkan RashadClifton David FullerAbdallah Sherif Radwan MohamedStephen Y LaiMax J H WitjesPublished in: Journal of personalized medicine (2022)
The volume of radiated bone was not predictive for risk of progression. The finding that recurrent ORN occurred with bone resection margins within the 56 Gy isodose volume suggests that this could serve as a starting point for the pre-operative planning of reducing the risk of ORN recurrence.