Ciliary Neurotrophic Factor Modulates Multiple Downstream Signaling Pathways in Prostate Cancer Inhibiting Cell Invasiveness.
Giovanni TossettaSonia FantoneRosaria GesuitaGaia GoteriMartina SenzacquaFabio MarcheggianiLuca TianoDaniela MarzioniRoberta MazzucchelliPublished in: Cancers (2022)
Our results showed that CNTF and CNTFRa were expressed in PCa and CRPC tissues and that CNTF has a pivotal role in prostate cancer environment remodeling and as a negative modulator of invasion processes of CRPC cell models.