Allergen extract- and component-based diagnostics in children of the ALLIANCE asthma cohort.

Chrysanthi SkevakiPavel TafoKathrin EiringhausNina TimmesfeldMarkus WeckmannChristine HapplePhilipp P NelsonNicole MaisonBianca SchaubIsabell RicklefsOliver FuchsErika von MutiusMatthias Volkmar KoppHarald RenzGesine HansenAnna-Maria Dittrichnull null

Published in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2021)

Among young children, the three sIgE assays showed good analytical and diagnostic concordance. Our results caution that the identification of larger numbers of sensitizations by more comprehensive multiplex approaches may not improve the clinical utility of sIgE testing in this age group.

Keyphrases

high throughput
allergic rhinitis
chronic obstructive pulmonary disease
young adults
lung function
oxidative stress
real time pcr
liquid chromatography
bioinformatics analysis
air pollution