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The roles of MTHFR (C677T, A1298C) and MGP (G-7A, T-138C) gene variations in development of diabetic nephropathy in patients with type 2 diabetes mellitus.

Arzu AyNevra AlkanliIdris KurtSedat ÜstündağTammam SipahiNecdet Sut
Published in: Journal of diabetes and metabolic disorders (2022)
In our study, although MTHFR and MGP gene variations were not risk factors, the GA-TT combined genotype of the MGP (G-7A/T-138C) gene variation was detected as an important risk factor for DN.
Keyphrases
  • diabetic nephropathy
  • risk factors
  • copy number
  • genome wide
  • genome wide identification
  • pet ct
  • dna methylation
  • transcription factor