A novel severe cerebral venous thrombosis rat model based on semi-ligation combined with ferric chloride and thrombin.
Lipo XiaoXun-Ming JiHaiping ZhaoYumin LuoShuyuan HuTingyu ZhaoZeliang HuJiangang DuanPublished in: CNS neuroscience & therapeutics (2022)
Semi-ligation combined with ferric chloride and thrombin can produce a severe CVST model with multiple venous sinus involvement, which is suitable for short- and long-term neurological and cognitive dysfunction assessment.