Neoadjuvant therapy does not impact the biliary microbiome in patients with pancreatic cancer.
Shay BehrensThomas Lee SuttonRanish K PatelIssac R SchwantesJack O'GradyAlicia JohnsonAaron GrossbergCharles LopezErin GilbertSkye MayoBrett C SheppardPublished in: Journal of surgical oncology (2023)
Biliary stenting is the greatest predictor for positive biliary cultures and SSIs in resected PDAC patients. Neither NAC nor radiotherapy impact bile culture positivity, speciation, rates, or antibiotic resistance patterns, and perioperative antibiotic prophylaxis should not differ.
Keyphrases
- end stage renal disease
- prognostic factors
- lymph node
- locally advanced
- newly diagnosed
- ejection fraction
- early stage
- rectal cancer
- radiation therapy
- cardiac surgery
- chronic kidney disease
- transcription factor
- patients undergoing
- radiation induced
- squamous cell carcinoma
- acute kidney injury
- mesenchymal stem cells
- antiplatelet therapy