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Effects of Zibotentan Alone and in Combination with Dapagliflozin on Fluid Retention in Patients with CKD.

J David SmeijerVictor S WasehuusNeeraj DhaunJose Luis Gorriz TeruelMaria José SolerMagnus ÅstrandAnne-Kristina MercierPeter J GreasleyPhilip AmberyHiddo J Lambers Heerspink
Published in: Journal of the American Society of Nephrology : JASN (2024)
High doses of zibotentan were associated with a higher risk of fluid retention, which was attenuated with lower doses and the addition of dapagliflozin.
Keyphrases
  • chronic kidney disease