Sustained Delivery of a Monoclonal Antibody against SARS-CoV-2 by Microencapsulated Cells: A Proof-of-Concept Study.

Assem AshimovaAskhat MyngbaySergey Yegorov Baurzhan Negmetzhanov Irina KadyrovaAngelina YershovaUlpan Kart Matthew S MillerGonzalo Hortelano

Published in: Pharmaceutics (2022)

We demonstrate here that cell microencapsulation is a viable approach to systemic delivery of intact SARS-CoV-2 mAb, with potential therapeutic applications that warrant further exploration.

Keyphrases

sars cov
monoclonal antibody
induced apoptosis
respiratory syndrome coronavirus
cell cycle arrest
single cell
endoplasmic reticulum stress
oxidative stress
pi k akt