Detection of anti-Trypanosoma cruzi antibodies by chimeric antigens in chronic Chagas disease-individuals from endemic South American countries.

Rodrigo Pimenta Del-ReiLeonardo Maia LeonyPaola Alejandra Fiorani CeledonNilson Ivo Tonin ZanchinMitermayer Galvão Dos ReisYara de Miranda GomesAlejandro Gabriel SchijmanSilvia Andrea LonghiFred Luciano Neves Santos

Published in: PloS one (2019)

Our findings showed a notable performance of IBMP-8.1 and -8.4 chimeric antigens in diagnosing chronic Chagas disease in individuals from endemic South American countries, confirming our hypothesis that these antigens could be used in geographical areas where distinct T. cruzi DTUs occur.

Keyphrases

trypanosoma cruzi
cell therapy
dendritic cells
stem cells
immune response
loop mediated isothermal amplification
label free