Phenome-wide association of 1809 phenotypes and COVID-19 disease progression in the Veterans Health Administration Million Veteran Program.

Rebecca J SongYuk-Lam HoPetra SchubertYojin ParkDaniel PosnerEmily M LordLauren CostaHanna GerlovinKatherine E KurganskyTori Anglin-FooteScott DuVallJennifer E HuffmanSaiju PyarajanJean C BeckhamKyong-Mi ChangKatherine P LiaoLuc DjousseDavid R GagnonStacey B WhitbourneRachel RamoniSumitra MuralidharPhilip S TsaoChristopher J O'DonnellJohn Michael GazianoJuan P CasasKelly Chonull null

Published in: PloS one (2021)

Older age, higher BMI, males and patients with a history of respiratory, kidney, bacterial or metabolic comorbidities experienced greater COVID-19 severity. Future studies to investigate the underlying mechanisms associated with these phenotype clusters and COVID-19 are warranted.

Keyphrases

coronavirus disease
sars cov
healthcare
public health
mental health
respiratory syndrome coronavirus
body mass index
physical activity
quality improvement
current status
weight gain
climate change
weight loss