Modulation of GSK-3 provides cellular and functional neuroprotection in the rd10 mouse model of retinitis pigmentosa.

Alonso Sánchez-CruzBeatriz Villarejo-ZoriMiguel MarchenaJosefa Zaldivar-DíezValle PalomoCarmen GilIgnacio LizasoainPedro de la VillaAna MartínezEnrique J de la RosaCatalina Hernández-Sánchez

Published in: Molecular neurodegeneration (2018)

These results provide proof of concept of the therapeutic potential of VP3.15 for the treatment of retinal neurodegenerative conditions in general, and RP in particular.

Keyphrases

mouse model
optical coherence tomography
diabetic retinopathy
signaling pathway
brain injury
pi k akt
cell proliferation
subarachnoid hemorrhage