Plasma Fibrinogen and sP-Selectin are Associated with the Risk of Lung Cancer in a Prospective Study.
Mirja GrafetstätterAnika HüsingSandra González MaldonadoDisorn SookthaiTheron JohnsonLaura Pletsch-BorbaVerena A KatzkeMichael HoffmeisterPeter BugertRudolf KaaksTilman KühnPublished in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2019)
The current prospective study supports the hypothesis of increased coagulation being a possible driver of lung carcinogenesis, as strong positive associations were found between two procoagulative markers, sP-Selectin and fibrinogen, with lung cancer risk. Both biomarkers could improve lung cancer risk prediction, but external validation of the results is needed.
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