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Resting heart rate and risk of dementia: a Mendelian randomization study in the international genomics of Alzheimer's Project and UK Biobank.

Xingxing ChenYi ZhengJun WangBlake YueXian ZhangKenta NakaiLijing L Yan
Published in: PeerJ (2024)
Our study did not find any evidence that supports a causal effect of RHR on dementia. Previous observational associations between RHR and dementia are likely attributed to the correlation between RHR and other cardiovascular diseases.
Keyphrases
  • heart rate
  • mild cognitive impairment
  • heart rate variability
  • cardiovascular disease
  • blood pressure
  • cognitive impairment
  • cognitive decline
  • metabolic syndrome
  • coronary artery disease