RNA Splicing Events in Circulation Distinguish Individuals with and without New-Onset Type 1 Diabetes.
Bobbie-Jo M Webb-RobertsonWenting WuJavier E FloresLisa M BramerFarooq SyedSarah A TerseySarah C MayEmily K SimsCarmella Evans-MolinaRaghavendra G MirmiraPublished in: The Journal of clinical endocrinology and metabolism (2024)
Alternative RNA splicing events in whole blood are significantly enriched in individuals with new-onset T1D and can effectively distinguish these individuals from unaffected controls. Our findings also suggest that RNA splicing profiles offer the potential to provide insights into disease pathogenesis.