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RNA Splicing Events in Circulation Distinguish Individuals with and without New-Onset Type 1 Diabetes.

Bobbie-Jo M Webb-RobertsonWenting WuJavier E FloresLisa M BramerFarooq SyedSarah A TerseySarah C MayEmily K SimsCarmella Evans-MolinaRaghavendra G Mirmira
Published in: The Journal of clinical endocrinology and metabolism (2024)
Alternative RNA splicing events in whole blood are significantly enriched in individuals with new-onset T1D and can effectively distinguish these individuals from unaffected controls. Our findings also suggest that RNA splicing profiles offer the potential to provide insights into disease pathogenesis.
Keyphrases
  • type diabetes
  • nucleic acid
  • insulin resistance
  • metabolic syndrome
  • climate change
  • adipose tissue