Synthesis and Photophysical Characterization of Azoheteroarenes.

Yongjin XuChunxia GaoJoakim Andréasson Morten Grøtli

Published in: Organic letters (2018)

A set of azoheteroarenes have been synthesized with Buchwald-Hartwig coupling and microwave-assisted O2 oxidation as the key steps. Several compounds exhibit good to excellent photoswitching properties (high switching efficiency, good fatigue resistance, and thermal stability of Z-isomer) relevant for photocontrolled applications, which pave the way for use in photopharmacology.

Keyphrases

hydrogen peroxide
electron transfer
room temperature
sleep quality
depressive symptoms
oxide nanoparticles