Impaired brain endocannabinoid tone in the activity-based model of anorexia nervosa.
Roberto ColluMaria SchermaFabiana PiscitelliElisa GiuntiValentina SattaM Paola CastelliRoberta VerdeWalter FrattaTiziana BisognoPaola FaddaPublished in: The International journal of eating disorders (2019)
These data demonstrate an altered brain eCB tone in ABA rats, further supporting the involvement of an impaired eCB system in AN pathophysiology that may contribute to the maintenance of some symptomatic aspects of the disease.