Musculoskeletal conditions may increase the risk of chronic disease: a systematic review and meta-analysis of cohort studies.

Amanda WilliamsSteven J KamperJohn H WiggersKate M O'BrienHopin LeeLuke WolfendenSze Lin YoongEmma RobsonJames H McAuleyJan HartvigsenChristopher M Williams

Published in: BMC medicine (2018)

This meta-analysis found that musculoskeletal conditions may increase the risk of chronic disease. In particular, osteoarthritis appears to increase the risk of developing cardiovascular disease. Prevention and early treatment of musculoskeletal conditions and targeting associated chronic disease risk factors in people with long standing musculoskeletal conditions may play a role in preventing other chronic diseases. However, a greater understanding about why musculoskeletal conditions may increase the risk of chronic disease is needed.

Keyphrases

cardiovascular disease
systematic review
risk factors
rheumatoid arthritis
type diabetes
metabolic syndrome
coronary artery disease
drug delivery
cancer therapy
replacement therapy