Relationship between adipokines, cognition, and brain structures in old age depending on obesity.

Junghee HaSeyul KwakKeun You KimHyunjeong KimSo Yeon ChoMinae KimJun-Young LeeEosu Kim

Published in: The journals of gerontology. Series A, Biological sciences and medical sciences (2022)

Obesity might be a factor that determines how adipokines affect brain structure and cognition. Leptin resistance might influence the relationship between adipokines and cognition. In addition, LAR rather than each adipokine levels alone may be a better indicator of AD risk in older adults with metabolic stress.

Keyphrases

white matter
insulin resistance
mild cognitive impairment
metabolic syndrome
weight loss
type diabetes
resting state
high fat diet induced
multiple sclerosis
weight gain
physical activity
functional connectivity
community dwelling
mass spectrometry
stress induced