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Thirty-day mortality rates after immunotherapy initiation.

Osman SütçüoğluAyşegül İlhanSeher Yildiz TacarDeniz Can GuvenGokhan UcarNuri KaradurmusFatih YildizEmrah EraslanDoğan UncuDeniz TuralAytuğ ÜnerNazan GünelNuriye OzdemirSaadettin KılıçkapÖmür Berna Çakmak ÖksüzoğluAhmet ÖzetOzan Yazıcı
Published in: Immunotherapy (2021)
Background: The aim of this study was to determine the cause of death in patients who died within 30 days after the first dose of immunotherapy. Methods: The data of 1432 patients treated with immunotherapy in six tertiary referral hospitals were retrospectively analyzed. Results: It was determined that 34 (2%) of the patients died within 30 days after the first dose of immunotherapy. Death occurred in all patients who received palliative therapy, and most patients (88%) received immunotherapy as second- or subsequent-line of therapy. The most common cause of death was disease progression and thromboembolic events. Conclusion: Preliminary results of the current study might give some clues to define the patient population in whom the fatal side effects of immunotherapy might be encountered.
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