Using superparamagnetic iron oxide nanoparticles to enhance bioavailability of quercetin in the intact rat brain.

Rezvan Enteshari NajafabadiNasrin KazemipourAbolghasem EsmaeiliSiamak BeheshtiSaeed Nazifi

Published in: BMC pharmacology & toxicology (2018)

The results of this study confirm that SPION as a targeted drug delivery system enhances the bioavailability of quercetin in the brain about ten folds higher than free quercetin and could be used for the treatment of neurodegenerative disorders.

Keyphrases

iron oxide nanoparticles
resting state
white matter
cancer therapy
functional connectivity
multiple sclerosis
combination therapy
smoking cessation
cerebral ischemia
blood brain barrier
brain injury