A comparison between p16-positive head and neck cancer of unknown primary (HPV-HNCUP) and oropharyngeal squamous cell carcinoma (HPV-OPSCC): are they the same disease?

Matthias BalkRobin RuppMatti SievertKonstantinos MantsopoulosMoritz AllnerPhilipp GrundtnerSarina K MuellerMarkus EcksteinHeinrich IroMarkus HechtAntoniu-Oreste Gostian

Published in: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery (2023)

The results presented demonstrate a significant reduced OS and DSS for HPV-HNCUP patients. Accordingly, in our study HPV-HNCUP and HPV-OPSCC are two different entities with a different oncological outcome.

Keyphrases

high grade
squamous cell carcinoma
cervical cancer screening
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
prostate cancer
radiation therapy
lymph node metastasis