Impact of the immune profiles of hypertensive patients with and without obesity on COVID-19 severity.
Renata Moll-BernardesJuliana R FerreiraAndréa Silvestre SousaMariana B TortellyAdriana L PimentelAna Cristina B S FigueiredoEduardo B SchaustzJosé Carlos Pizzolante SeccoAllan Robson Kluser SalesFlavia V O TerziAdriana Xavier de BritoRenée O SarmentoMarcia M Noya-RabeloSergio FortierFlavia A Matos E SilvaNarendra VeraLuciana CondeMauro Jorge Cabral-CastroDenilson C AlbuquerquePaulo Rosado de-CastroGabriel C CamargoMartha V T PinheiroOlga F SouzaFernando A BozzaRonir R LuizEmiliano MedeiPublished in: International journal of obesity (2005) (2023)
Our findings suggest that clinical and immune variables and obesity interact synergistically to increase the COVID-19 progression risk. The immune signatures of hypertensive patients with and without obesity severe COVID-19 highlight differences in immune dysregulation mechanisms, with potential therapeutic applications.