Characterisation of Levonorgestrel-Resistant Endometrial Cancer Cells.

Molly DoreSara FilocheKirsty DanielsonClaire E Henry

Published in: Cancer management and research (2021)

LNG-resistant cells may have more oncogenic potential than their LNG-sensitive counterparts. Significant changes in the mRNA expression of KLF4 and SATB2 of LNG-resistant cells is a promising preliminary result in biomarker discovery for guiding LNG-IUS treatment of early stage endometrial cancer.

Keyphrases

endometrial cancer
induced apoptosis
early stage
cell cycle arrest
transcription factor
signaling pathway
oxidative stress
risk assessment
climate change
combination therapy
human health
replacement therapy
sentinel lymph node