Impact of conditioning intensity on outcomes of haploidentical stem cell transplantation for patients with acute myeloid leukemia 45 years of age and over.
Nicole SantoroMyriam LabopinFabio CiceriMaria Teresa Van LintDaniela NassoDidier BlaiseWilliam ArceseJohanna TischerBenedetto BrunoGerhard EhningerYener KocStella SantaroneXiao-Jun HuangBipin P SavaniMohamad MohtyAnnalisa RuggeriArnon NaglerPublished in: Cancer (2019)
No differences were found between MAC and RIC regimens for haplo-SCT in adults with AML who were ≥45 years of age. The type of GVHD prophylaxis, disease status, and performance status were the major predictors of transplantation outcome. These results may serve as the background for randomized study comparing RIC versus MAC for haplo-SCT in adults with AML.