Rare variant association analyses reveal the significant contribution of carbohydrate metabolic disturbance in severe adolescent idiopathic scoliosis.

Wen WenZhengye ZhaoZhifa ZhengSen ZhaoHengqiang ZhaoXi ChengHuakang DuZiquan LiShengru WangGuixing QiuZhihong WuTerry Jianguo ZhangNan Wu

Published in: Journal of medical genetics (2024)

This study uncovers the pivotal role of genetic variants in carbohydrate metabolism in the development of AIS, unveiling new insights into its aetiology and potential treatment.

Keyphrases

early onset
genome wide
gene expression
combination therapy
climate change