Evaluation of the Langerhans cells role in vitiligo and its relationship to NB-UVB.

Mohammed ShoeibAzza Gaber Antar FaragMona EltorgmanAsmaa Gaber Abdou

Published in: Journal of cosmetic dermatology (2021)

Reduction in LCs in vitiligo may be a sign of active disease and melanocytes destruction. The percentage of LCs affects response to NB-UVB since higher percentage is associated with greater response to therapy. Therefore, modulation of LCs as a type of immunotherapy could be beneficial in improvement of vitiligo.

Keyphrases

induced apoptosis
cell cycle arrest
oxidative stress
stem cells
endoplasmic reticulum stress
pi k akt