Active immunization with norovirus P particle-based amyloid-β chimeric protein vaccine induces high titers of anti-Aβ antibodies in mice.
Ping YangYongqing GuoYao SunBin YuHaihong ZhangJiaxin WuXianghui YuHui WuWei KongPublished in: BMC immunology (2019)
The untagged Aβ1-6 chimeric protein vaccine is safe and highly immunogenic. Further research will determine the efficacy in cognitive improvement and disease progression delay.