Variation in Mean Arterial Pressure Increases Falls Risk in Elderly Physically Frail and Prefrail Individuals Treated With Antihypertensive Medication.
Sultana Monira HussainMichael E ErnstAnna L BarkerKaren L MargolisChristopher M ReidJohannes Tobias NeumannAndrew M TonkinLe Thi Phuong ThaoLawrence J BeilinThao PhamEnayet K ChowdhuryFlavia M CicuttiniJulia F M Gilmartin-ThomasPrudence R CarrJohn J McNeilPublished in: Hypertension (Dallas, Tex. : 1979) (2022)
Higher levels of long-term variability in MAP increase the risk of serious falls in older frail and prefrail individuals taking antihypertensive medications. The observation that the relationship was limited to frail and prefrail individuals might explain some of the variability of previous studies linking blood pressure indices and falls.