Login / Signup

Modulation of histone H3K4 dimethylation by spermidine ameliorates motor neuron survival and neuropathology in a mouse model of ALS.

Seung-Hye ChoiAli Yousefian-JaziSeung Jae HyeonPhuong Thi Thanh NguyenJiyeon ChuSojung KimSuhyun KimHannah L RyuNeil W KowallHoon RyuJunghee Lee
Published in: Journal of biomedical science (2022)
Together, modulating epigenetic targets such as LSD1 by small compounds may be a useful therapeutic strategy for treating ALS.
Keyphrases
  • mouse model
  • dna methylation
  • amyotrophic lateral sclerosis
  • gene expression
  • signaling pathway
  • free survival