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Cichorium intybus L. Extract Suppresses Experimental Gout by Inhibiting the NF-κB and NLRP3 Signaling Pathways.

Yu WangZhijian LinBing ZhangZhuoxi JiangFanfan GuoTing Yang
Published in: International journal of molecular sciences (2019)
This study suggests that chicory extract and chicoric acid may be used as promising therapeutic agents against gout by inhibiting the NF-κB and NLRP3 signaling pathways.
Keyphrases
  • signaling pathway
  • pi k akt
  • induced apoptosis
  • epithelial mesenchymal transition
  • uric acid
  • oxidative stress
  • anti inflammatory
  • lps induced
  • immune response
  • inflammatory response