Clinical validation of the upper face first principle-A clinical, prospective, interventional split-face study.
Claudia A HernandezDavid E Uribe ZapataMaria Paula BermudezKonstantin FrankNicholas MoellhoffMichael G AlfertshoferRobert H GotkinKristina DavidovicSebastian CotofanaPublished in: Journal of cosmetic dermatology (2022)
Applying the upper face first injection algorithm seems to result in better aesthetic outcomes when directly compared to the lower face first algorithm. Semiquantitative and objective outcome measurements confirm its clinical effectiveness.