Microenvironmental changes induced by placenta-derived mesenchymal stem cells restore ovarian function in ovariectomized rats via activation of the PI3K-FOXO3 pathway.
Jong Ho ChoiJin SeokSeung Mook LimTae Hee KimGi Jin KimPublished in: Stem cell research & therapy (2020)
Taken together, these results show that PD-MSC Tx can restore ovarian function and induce ovarian folliculogenesis via the PI3K/Akt and FOXO signaling pathway.