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A rare canonical splice-site variant in VPS13B causes attenuated Cohen syndrome.

Malena Daich VarelaFabiana Louise MottaAndrew R WebsterGavin Arno
Published in: Ophthalmic genetics (2021)
Exon 31 skipping in VPS13B may lead to a hypomorphic change, with partial gene function and an incomplete, mild Cohen syndrome-like phenotype.
Keyphrases
  • case report
  • genome wide
  • copy number
  • gene expression
  • transcription factor